Doubt on Anti-Aging Molecule as Drug Trial Stops

January 11, 2011 | Source: New York Times

Pharmaceutical company Sirtris announced last month that it had halted the last of its clinical trials of resveratrol, the minor ingredient of red wine that some researchers see as a drug that can extend life, but the co-founders of Sirtris, David Sinclair and Christoph Westphal, retain their confidence in the drug.

Resveratrol has several features that make it unsuitable as a drug, Sirtris CEO George Vlasuk said. These include the fact that it is hard to maintain a consistent level of resveratrol in the bloodstream, it seems to have different effects at different doses, and it is not patentable.