How to deliver DNA into cells without triggering immune responses

June 26, 2008 | Source: KurzweilAI

University of Georgia researchers have used self-assembling small peptides (short chains of amino acids, which bind to genes and mimic proteins) packaged in a biocompatible polymer scaffold to deliver DNA into cells (for gene therapy) without triggering immune responses (such as allergies and anaphylactic shock).

Modified viruses are currently the most efficient vector (delivery package) for gene therapy, but they can cause serious complications if the immune system is triggered by the virus.

University of Georgia News Release

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